Not all placental allograftsare created equal

The differences in preservation matter

Placental allografts have been used for over a century—the fetal membrane was first used for the transplantation of skin in 1910. As innovations were made over time, the preservation methods can vary with each commercially available product.

Some manufacturers remove part of the placental membrane—including the amnion, chorion, epithelium, or spongy layer—which also removes important components and alters the native tissue composition.

The more a placental allograft is processed, including the removal of layers, the more limited the ECM protein content for use as a protective barrier. Preserving more layers retains the native tissue composition including structural proteins for use as a protective barrier.